Overview of milling techniques for improving the solubility of poorly water-soluble drugs

• Main Authors: Zhi Hui Loh (Author), Asim Kumar Samanta (Author), Paul Wan Sia Heng (Author)
• Formato: Livro
• Publicado em: Elsevier, 2015-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Milling involves the application of mechanical energy to physically break down coarse particles to finer ones and is regarded as a "top-down" approach in the production of fine particles. Fine drug particulates are especially desired in formulations designed for parenteral, respiratory and...