Incorporation of Escherichia coli heat-labile enterotoxin B subunit into rabies virus particles enhances its immunogenicity in mice and dogs

• Main Authors: Zhiyuan Gong (Author), Hailun Li (Author), Meichen Qian (Author), Yujie Bai (Author), Hongli Jin (Author), Jingxuan Sun (Author), Mengyao Zhang (Author), Cuicui Jiao (Author), Pei Huang (Author), Yuanyuan Li (Author), Haili Zhang (Author), Hualei Wang (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although inactivated vaccines against rabies have the advantage of high safety, effective protection against rabies virus (RABV) infection often requires multiple, high-dose immunization. Incorporating a molecular adjuvant into the viral particles has been found to be a useful strategy to promote th...