Trimetazidine prevents diabetic cardiomyopathy by inhibiting Nox2/TRPC3-induced oxidative stress

Diabetic cardiomyopathy (DCM) is characterized by cardiac hypertrophy, fibrosis, oxidative stress and inflammation. Trimetazidine (TMZ), a potent metabolism modulator, has been shown to be cardioprotective in experimental models of ischaemia-reperfusion and type 2 diabetes-induced cardiomyopathy. Th...

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Main Authors: Sheng-Gao Tang (Author), Xiao-Yu Liu (Author), Shan-Ping Wang (Author), Hong-Hui Wang (Author), Aleksandar Jovanović (Author), Wen Tan (Author)
Format: Book
Published: Elsevier, 2019-04-01T00:00:00Z.
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3rd Floor Main Library

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