Trans-Chalcone Attenuates Pain and Inflammation in Experimental Acute Gout Arthritis in Mice

• Main Authors: Larissa Staurengo-Ferrari (Author), Kenji W. Ruiz-Miyazawa (Author), Felipe A. Pinho-Ribeiro (Author), Victor Fattori (Author), Tiago H. Zaninelli (Author), Stephanie Badaro-Garcia (Author), Sergio M. Borghi (Author), Thacyana T. Carvalho (Author), Jose C. Alves-Filho (Author), Thiago M. Cunha (Author), Fernando Q. Cunha (Author), Rubia Casagrande (Author), Waldiceu A. Verri (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gouty arthritis is characterized by an intense inflammatory response to monosodium urate crystals (MSU), which induces severe pain and reduction in the life quality of patients. Trans-Chalcone (1,3-diphenyl-2-propen-1-one) is a flavonoid precursor presenting biological activities such as anti-inflam...