Metabolomic architecture of obesity implicates metabolonic lactone sulfate in cardiometabolic disease

• Main Authors: Swapan K. Das (Author), Hannah C. Ainsworth (Author), Latchezar Dimitrov (Author), Hayrettin Okut (Author), Mary E. Comeau (Author), Neeraj Sharma (Author), Maggie C.Y. Ng (Author), Jill M. Norris (Author), Yii-der I. Chen (Author), Lynne E. Wagenknecht (Author), Donald W. Bowden (Author), Fang-Chi Hsu (Author), Kent D. Taylor (Author), Carl D. Langefeld (Author), Nicholette D. Palmer (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Identify and characterize circulating metabolite profiles associated with adiposity to inform precision medicine. Methods: Untargeted plasma metabolomic profiles in the Insulin Resistance Atherosclerosis Family Study (IRASFS) Mexican American cohort (n = 1108) were analyzed for associatio...