Improved Performance of Anti-miRNA Oligonucleotides Using a Novel Non-Nucleotide Modifier
Anti-microRNA oligonucleotides (AMOs) are steric blocking antisense reagents that inhibit microRNA (miRNA) function by hybridizing and repressing the activity of a mature miRNA. First generation AMOs employed 2'-O-Methyl RNA nucleotides (2'OMe) with phosphorothioate (PS) internucleotide li...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2013-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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