A first‐in‐human phase I study of SHR‐1906, a humanized monoclonal antibody against connective tissue growth factor, in healthy participants

• Main Authors: Lin‐Lin Song (Author), Hai‐Yan Zhou (Author), Pan‐Pan Ye (Author), Qian Li (Author), Ke‐Guang Chen (Author), Ye‐Hui Zhang (Author), Fu‐Rong Zhao (Author), Jin‐Yi Shi (Author), Yuan Luo (Author), Min Zhu (Author), Jian‐Jun Zhang (Author), Xin‐Mei Yang (Author), Wei Zhao (Author)
• Format: Book
• Published: Wiley, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract New therapeutic targets and drugs are urgently needed to halt the fibrosing process in idiopathic pulmonary fibrosis (IPF). SHR‐1906 is a novel fully humanized monoclonal antibody against the connective tissue growth factor, which plays an essential role in the genesis of IPF. We assessed t...