Association of IL-10-592 C > A /-1082 A > G and the TNFα -308 G > A with susceptibility to COVID-19 and clinical outcomes

• Main Authors: Raghda E. Eldesouki (Author), Rania M. Kishk (Author), Noha M. Abd El-Fadeal (Author), Rama I Mahran (Author), Noha Kamel (Author), Eman Riad (Author), Nader Nemr (Author), Safaa M. Kishk (Author), Eman Abdel-Moemen Mohammed (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Variation in host immune responses to SARS-CoV-2 is regulated by multiple genes involved in innate viral response and cytokine storm emergence like IL-10 and TNFa gene polymorphisms. We hypothesize that IL-10; -592 C > A and − 1082 A > G and TNFa-308 G > A are associated...