Supersaturable organic-inorganic hybrid matrix based on well-ordered mesoporous silica to improve the bioavailability of water insoluble drugs

• Main Authors: Qiaoli Wu (Author), Disang Feng (Author), Zhengwei Huang (Author), Minglong Chen (Author), Dan Yang (Author), Xin Pan (Author), Chao Lu (Author), Guilan Quan (Author), Chuanbin Wu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesoporous silica with uniform 2-D hexagonal pores has been newly employed as facile reservoir to impove the dissolution rate of water insoluble drugs. However, rapid drug release from mesoporous silica is usually accompanied by the generation of supersaturated solution, which leads to the drug prec...