DEEPCYPs: A deep learning platform for enhanced cytochrome P450 activity prediction

• Main Authors: Daiqiao Ai (Author), Hanxuan Cai (Author), Jiajia Wei (Author), Duancheng Zhao (Author), Yihao Chen (Author), Ling Wang (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Cytochrome P450 (CYP) is a superfamily of heme-containing oxidizing enzymes involved in the metabolism of a wide range of medicines, xenobiotics, and endogenous compounds. Five of the CYPs (1A2, 2C9, 2C19, 2D6, and 3A4) are responsible for metabolizing the vast majority of approved drugs. Adverse dr...