Anisodamine (654-1/654-2) ameliorates septic kidney injury in rats by inhibiting inflammation and apoptosis

• Principais autores: Dong Liu (Autor), Fei Tang (Autor), Li Zhang (Autor), Feng Wan (Autor), Li-Yue Xu (Autor), Jing-Nan Zhang (Autor), Xiao-Lan Zhao (Autor), Hui Ao (Autor), Cheng Peng (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

IntroductionTo investigate the protective effects of anisodamine (654-1/654-2) against acute kidney injury (AKI) in LPS-induced septic shock rats and explore its molecular mechanisms.Methods56 rats were randomly divided into 8 groups: control, LPS, LPS + 654-1, and LPS + 654-2 (1.25, 2.5 and 5 mg/kg...