Anisodamine (654-1/654-2) ameliorates septic kidney injury in rats by inhibiting inflammation and apoptosis

• Main Authors: Dong Liu (Author), Fei Tang (Author), Li Zhang (Author), Feng Wan (Author), Li-Yue Xu (Author), Jing-Nan Zhang (Author), Xiao-Lan Zhao (Author), Hui Ao (Author), Cheng Peng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionTo investigate the protective effects of anisodamine (654-1/654-2) against acute kidney injury (AKI) in LPS-induced septic shock rats and explore its molecular mechanisms.Methods56 rats were randomly divided into 8 groups: control, LPS, LPS + 654-1, and LPS + 654-2 (1.25, 2.5 and 5 mg/kg...