Aptamer-Gemcitabine Conjugates with Enzymatically Cleavable Linker for Targeted Delivery and Intracellular Drug Release in Cancer Cells

Gemcitabine is a chemotherapeutic used clinically to treat a variety of cancers. However, because it lacks tumor cell specificity, gemcitabine may cause off-target cytotoxicity and adversely impact patients. To impart cancer cell specificity to gemcitabine and improve its therapeutic efficacy, we sy...

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主要な著者: Jianjun Qi (著者), Zihua Zeng (著者), Zhenghu Chen (著者), Cole Nipper (著者), Xiaohui Liu (著者), Quanyuan Wan (著者), Jian Chen (著者), Ching-Hsuan Tung (著者), Youli Zu (著者)
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出版事項: MDPI AG, 2022-04-01T00:00:00Z.
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3rd Floor Main Library

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