4-(Indol-3-yl)thiazole-2-amines and 4-ιndol-3-yl)thiazole Acylamines as Νovel Antimicrobial Agents: Synthesis, In Silico and In Vitro Evaluation

• Main Authors: Sergei Simakov (Author), Victor Kartsev (Author), Anthi Petrou (Author), Ioannis Nicolaou (Author), Athina Geronikaki (Author), Marija Ivanov (Author), Marina Kostic (Author), Jasmina Glamočlija (Author), Marina Soković (Author), Despoina Talea (Author), Ioannis S. Vizirianakis (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This manuscript deals with the synthesis and computational and experimental evaluation of the antimicrobial activity of twenty-nine 4-(indol-3-yl)thiazole-2-amines and 4-ιndol-3-yl)thiazole acylamines. An evaluation of antibacterial activity against Gram (+) and Gram (−) bacteria revealed that the M...