Cover Image

4-(Indol-3-yl)thiazole-2-amines and 4-ιndol-3-yl)thiazole Acylamines as Νovel Antimicrobial Agents: Synthesis, In Silico and In Vitro Evaluation

This manuscript deals with the synthesis and computational and experimental evaluation of the antimicrobial activity of twenty-nine 4-(indol-3-yl)thiazole-2-amines and 4-ιndol-3-yl)thiazole acylamines. An evaluation of antibacterial activity against Gram (+) and Gram (−) bacteria revealed that the M...

Full description

Saved in:

Bibliographic Details
Main Authors:	Sergei Simakov (Author), Victor Kartsev (Author), Anthi Petrou (Author), Ioannis Nicolaou (Author), Athina Geronikaki (Author), Marija Ivanov (Author), Marina Kostic (Author), Jasmina Glamočlija (Author), Marina Soković (Author), Despoina Talea (Author), Ioannis S. Vizirianakis (Author)
Format:	Book
Published:	MDPI AG, 2021-10-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Synthesis and Antimicrobial Activity of New Heteroaryl(aryl) Thiazole Derivatives Molecular Docking Studies
by: Victor Kartsev, et al.
Published: (2022)

The synthesis of N-(4-aryl-thiazol-2-yl)-N1-(4,5,6,7-tetrahydro-3H-azepin-2-yl)-hydrazine hydrobromides and the cardioprotective activity of (41-methoxyphenyl-thiazol-2-yl) derivative
by: Sergii А. Demchenko, et al.
Published: (2021)

(Hetero)aryl substituted thiazol-2,4-yl scaffold as human carbonic anhydrase I, II, VII and XIV activators
by: Marouan Rami, et al.
Published: (2019)

QSAR-analysis of 1-[2-(R-phenylimino)-4-methyl-3-(3-[morpholine-4-yl]propyl)-2,3-dihydro-1,3-thiazol-5-yl]ethane-1-one's derivatives as potential antioxidants
by: Іryna Drapak, et al.
Published: (2019)

Modification of 4-(4-chlorothiophen-2-yl)thiazol-2-amine derivatives for the treatment of analgesia and inflammation: synthesis and in vitro, in vivo, and in silico studies
by: Mater H. Mahnashi, et al.
Published: (2024)

Novel N-(pyrimidin-4-yl)thiazol-2-amine derivatives as dual-action hypoglycemic agents that activate GK and PPARγ
by: Hui-peng Song, et al.
Published: (2011)

3-Amino-5-(indol-3-yl)methylene-4-oxo-2-thioxothiazolidine Derivatives as Antimicrobial Agents: Synthesis, Computational and Biological Evaluation
by: Volodymyr Horishny, et al.
Published: (2020)

Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights
by: Al-Warhi T, et al.
Published: (2022)

<i>N</i>-Derivatives of (<i>Z</i>)-Methyl 3-(4-Oxo-2-thioxothiazolidin-5-ylidene)methyl)-1<i>H</i>-indole-2-carboxylates as Antimicrobial Agents-In Silico and In Vitro Evaluation
by: Anthi Petrou, et al.
Published: (2023)

1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders
by: Ondrej Benek, et al.
Published: (2018)

Synthesis and evaluation of novel 1-(((6-substitutedbenzo[d]thiazol-2-yl)amino)(heteroaryl)methyl)naphthalen-2-ol as pesticidal agents
by: Junfeng Shang, et al.
Published: (2022)

Synthesis and cytotoxic evaluation of some novel 3-[2-(2-phenyl-thiazol-4-yl)-ethyl] -3H-pyrido [2,3-d]pyrimidin-4-one derivatives
by: Marzieh Rahmani Khajouei, et al.
Published: (2021)

Synthesis and antitumor properties of some new N-(5-R-benzyl-1,3-thiazol-2-yl)-4,5-dihydro-1H-imidazole-2-carboxamides
by: Volodymyr Ya Horishny, et al.
Published: (2020)

Thiazole-Bearing 4-Thiazolidinones as New Anticonvulsant Agents
by: Mariia Mishchenko, et al.
Published: (2020)

Search for angiotensin II receptor antagonists among 4-aryl-n-(aryl)-3-(prop-2-en-1-yl)-2,3-dihydro-1,3-thiazol-2-imine derivatives
by: Iryna Drapak, et al.
Published: (2019)

2-((1H-Benzo[d]imidazol-2-yl)amino)benzo[d]thiazole-6-sulphonamides: a class of carbonic anhydrase II and VII-selective inhibitors
by: Morteza Abdoli, et al.
Published: (2023)

Synthesis of [11C]carbonyl-labeled cyclohexyl (5-(2-acetamidobenzo[d]thiazol-6-yl)-2-methylpyridin-3-yl)carbamate ([11C-carbonyl]PK68) as a potential PET tracer for receptor-interacting protein 1 kinase
by: Tomoteru Yamasaki, et al.
Published: (2022)

Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles
by: Lakshmana Rao Krishna Rao Ravindranath, et al.
Published: (2013)

Synthesis and cytotoxicity evaluation of thiosemicarbazones and their thiazole derivatives
by: Saulo Feheiberg Pinto Braga, et al.

Synthesis, in-vitro antimicrobial and antitubercular screening of Schiff bases of 3-amino-1-phenyl-4- [2-(4-phenyl-1,3-thiazol-2-yl) hydrazin-1-ylidene]-4,5-dihydro-1H-pyrazol-5-one
by: K K Sivakumar, et al.
Published: (2013)

Novel Thiazolidine-2,4-dione-trimethoxybenzene-thiazole Hybrids as Human Topoisomerases Inhibitors
by: Maria Stefania Sinicropi, et al.
Published: (2023)

Synthesis and biological evaluation of thiazole derivatives as LbSOD inhibitors
by: Camila C. Bitencourt Brito, et al.
Published: (2019)

Synthesis and antimicrobial evaluation with DFT study for new thiazole derivatives
by: Sumayah Saadi Abbas, et al.
Published: (2018)

Synthesis and anаlgеsic properties of (3-allyl-4-aryl-3H-thiazol-2-ylidene)-[4-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)phenyl]amine derivatives
by: S. A. Demchenko, et al.
Published: (2018)

Synthesis, Characterization and Antimicrobial Evaluation with DFT Study of New Two-Amino-4-(4-Chlorophenyl) Thiazole Derivatives
by: Ammar A Mahmood Kubba, et al.
Published: (2018)

Thiazole-Based Thiosemicarbazones: Synthesis, Cytotoxicity Evaluation and Molecular Docking Study
by: Gomha SM, et al.
Published: (2021)

One-Pot Synthesis of Novel Thiazoles as Potential Anti-Cancer Agents
by: Sayed AR, et al.
Published: (2020)

A review on progress of thiazole derivatives as potential anti-inflammatory agents
by: Kereyagalahally H. Narasimhamurthy, et al.
Published: (2024)

Experimental and In Silico Evaluation of New Heteroaryl Benzothiazole Derivatives as Antimicrobial Agents
by: Alexander Zubenko, et al.
Published: (2022)

Assessment of anti-diabetic activity of a novel hydrazine-thiazole derivative: in vitro and in vivo method
by: Marina Ferrara de Resende, et al.

Thiopyrano[2,3-d]Thiazoles as New Efficient Scaffolds in Medicinal Chemistry
by: Anna Kryshchyshyn, et al.
Published: (2018)

Evaluation of the interference of platelets in reticulocyte counting by flow cytometry using thiazole orange
by: Karina Augusta Viana, et al.

Synthesis of New Thiazole Derivatives Bearing Thiazolidin-4(5H)-One Structure and Evaluation of Their Antimicrobial Activity
by: Asaf Evrim Evren, et al.
Published: (2022)

Synthesis and cytotoxicity evaluation of some new 6-nitro derivatives of thiazole-containing 4-(3H)-quinazolinone
by: Leila Hosseinzadeh, et al.
Published: (2016)

Antimicrobial Activity of Catechol-Containing Biopolymer Poly[3-(3,4-dihydroxyphenyl)glyceric Acid] from Different Medicinal Plants of Boraginaceae Family
by: Vakhtang Barbakadze, et al.
Published: (2023)

The study of analgesic effect of 5-(furan-2-yl, 2-methylfuran-3-yl)-4-amino-1,2,4-triazole-3-thion derivatives
by: D. M. Danilchenko
Published: (2018)

Antifatigue action of the 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thione alkyl derivatives
by: D. M. Danilchenko, et al.
Published: (2018)

Synthesis of New Thiazole-Privileged Chalcones as Tubulin Polymerization Inhibitors with Potential Anticancer Activities
by: Hamada Hashem, et al.
Published: (2024)

Synthesis of tetrazole hybridized with thiazole, thiophene or thiadiazole derivatives, molecular modelling and antimicrobial activity
by: Matokah M. Abualnaja, et al.
Published: (2024)

Antibacterial activity of 3-methylbenzo[d]thiazol-methylquinolinium derivatives and study of their action mechanism
by: Ning Sun, et al.
Published: (2018)