Formulation, Optimization and Characterization of Chitosan Monodisperse Microparticles for Sustained Delivery of Hydrochlorothiazide HCl

• Main Authors: Jahanzeb Mudassir (Author), Aruba Khan Sherwani (Author), Amjad Hussain (Author), Nasir Abbas (Author), Muhammad sohail Arshad (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Hydrochlorothiazide HCl (HCTZ) is first line medication in the management of hypertension, however its poor solubility and GI irritation warrants long term application. The aim of present study was to prepare hydrochlorothiazide HCl (HCTZ) loaded monodisperse microparticles of chitosan (...