The spatial impact of a Western diet in enriching Galectin-1-regulated Rho, ECM, and SASP signaling in a novel MASH-HCC mouse model

• Główni autorzy: Tahereh Setayesh (Autor), Ying Hu (Autor), Farzam Vaziri (Autor), Dongguang Wei (Autor), Yu-Jui Yvonne Wan (Autor)
• Format: Książka
• Wydane: BMC, 2024-10-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background Hepatocellular carcinoma (HCC) arising from metabolic dysfunction-associated steatohepatitis (MASH) presents a significant clinical challenge, particularly given the prevalence of the Western diet (WD). The influence of diet on the tumor microenvironment remains poorly understood...