Biological evaluation and in silico studies of novel compounds as potent TAAR1 agonists that could be used in schizophrenia treatment

• Main Authors: Yunjie Wang (Author), Zhaofeng Liu (Author), Jing Lu (Author), Wenyan Wang (Author), Lin Wang (Author), Yifei Yang (Author), Hongbo Wang (Author), Liang Ye (Author), Jianzhao Zhang (Author), Jingwei Tian (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Schizophrenia is a serious mental illness that requires effective treatment with minimal adverse effects. As preclinical and clinical research progresses, trace amine-associated receptor 1 (TAAR1) is becoming a potential new target for the treatment of schizophrenia.Methods: We used mo...