Analgesic effect of GT-0198, a structurally novel glycine transporter 2 inhibitor, in a mouse model of neuropathic pain

• المؤلفون الرئيسيون: Yu Omori (مؤلف), Mayumi Nakajima (مؤلف), Kazumi Nishimura (مؤلف), Eiki Takahashi (مؤلف), Tadamasa Arai (مؤلف), Masato Akahira (مؤلف), Tomohiko Suzuki (مؤلف), Mie Kainoh (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2015-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

This study was conducted to identify the characteristic pharmacological features of GT-0198 that is phenoxymethylbenzamide derivatives. GT-0198 inhibited the function of glycine transporter 2 (GlyT2) in human GlyT2-expressing HEK293 cells and did not bind various major transporters or receptors of n...