TNF-α blockade suppresses pericystic inflammation following anthelmintic treatment in porcine neurocysticercosis.

• Main Authors: Siddhartha Mahanty (Author), Miguel A Orrego (Author), Carla Cangalaya (Author), M Paz Adrianzen (Author), Gianfranco Arroyo (Author), Juan Calcina (Author), Armando E Gonzalez (Author), Héctor H García (Author), Cristina Guerra-Giraldez (Author), Theodore E Nash (Author), Cysticercosis Working Group in Peru (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neurocysticercosis (NCC) is an infection of the brain with the larval cyst of the tapeworm, Taenia solium. Cysticidal treatment induces parasite killing resulting in a post inflammatory response and seizures, which generally requires corticosteroid treatment to control inflammation. The nature of th...