Development, Optimization, and Validation of an <i>in vitro</i> Cell-Based Bioassay to Determine the Biological Activity of Teriparatide (PTH1-34)

• Main Authors: Tao Luo (Author), Jianguang Lu (Author), Chen Guo (Author), Xue Feng (Author), Jun Xu (Author), Jun Feng (Author)
• פורמט: ספר
• יצא לאור: Georg Thieme Verlag KG, 2024-09-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

This study aimed to establish an efficient in vitro cell-based assay to measure the activity of teriparatide (PTH1-34). In this study, a rat osteosarcoma cell line (UMR-106) was treated with various concentrations of PTH1-34, and the biological activity of PTH1-34 was determined by quantitatively me...