Vanillic Acid Reduces Pain-Related Behavior in Knee Osteoarthritis Rats Through the Inhibition of NLRP3 Inflammasome-Related Synovitis

• Päätekijät: Zhenyuan Ma (Tekijä), Zhengquan Huang (Tekijä), Li Zhang (Tekijä), Xiaochen Li (Tekijä), Bo Xu (Tekijä), Yancheng Xiao (Tekijä), Xiaoqing Shi (Tekijä), Haosheng Zhang (Tekijä), Taiyang Liao (Tekijä), Peimin Wang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Objectives: Synovitis plays an important role in knee osteoarthritis (KOA) pain. The activation of the NOD-like receptor protein 3 (NLRP3) inflammasome in fibroblast-like synoviocytes (FLSs) promotes KOA development. In this study, we aimed to investigate whether vanillic acid (VA), a monomer derive...