Total Phenytoin concentration is not well correlated with active free drug in critically-ill head trauma patients

• Główni autorzy: Kourosh Sadeghi (Autor), Farin Hadi (Autor), Arezoo Ahmadi (Autor), Hadi Hamishehkar (Autor), Mohammad-Taghi Beigmohammadi (Autor), Ata Mahmoodpoor (Autor), Mohammad Reza Rouini (Autor), Shirin Farhudi (Autor), Narjes Hendoui (Autor), Atabak Najafi (Autor), Mojtaba Mojtahedzadeh (Autor)
• Format: Książka
• Wydane: Wolters Kluwer Medknow Publications, 2013-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Objective: Phenytoin is an antiepileptic drug used widely for prophylaxis and treatment of seizure after neurotrauma. Phenytoin has a complex pharmacokinetics and monitoring of its serum concentrations is recommended during treatment. Total phenytoin concentration is routinely measured for monitorin...