Total Phenytoin concentration is not well correlated with active free drug in critically-ill head trauma patients

• Asıl Yazarlar: Kourosh Sadeghi (Yazar), Farin Hadi (Yazar), Arezoo Ahmadi (Yazar), Hadi Hamishehkar (Yazar), Mohammad-Taghi Beigmohammadi (Yazar), Ata Mahmoodpoor (Yazar), Mohammad Reza Rouini (Yazar), Shirin Farhudi (Yazar), Narjes Hendoui (Yazar), Atabak Najafi (Yazar), Mojtaba Mojtahedzadeh (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wolters Kluwer Medknow Publications, 2013-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Objective: Phenytoin is an antiepileptic drug used widely for prophylaxis and treatment of seizure after neurotrauma. Phenytoin has a complex pharmacokinetics and monitoring of its serum concentrations is recommended during treatment. Total phenytoin concentration is routinely measured for monitorin...