Engineered Extracellular Vesicles/Exosomes as a New Tool against Neurodegenerative Diseases

• Main Authors: Flavia Ferrantelli (Author), Chiara Chiozzini (Author), Patrizia Leone (Author), Francesco Manfredi (Author), Maurizio Federico (Author)
• Format: Book
• Published: MDPI AG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neurodegenerative diseases are commonly generated by intracellular accumulation of misfolded/aggregated mutated proteins. These abnormal protein aggregates impair the functions of mitochondria and induce oxidative stress, thereby resulting in neuronal cell death. In turn, neuronal damage induces chr...