Engineered Extracellular Vesicles/Exosomes as a New Tool against Neurodegenerative Diseases

• Autors principals: Flavia Ferrantelli (Autor), Chiara Chiozzini (Autor), Patrizia Leone (Autor), Francesco Manfredi (Autor), Maurizio Federico (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2020-06-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Neurodegenerative diseases are commonly generated by intracellular accumulation of misfolded/aggregated mutated proteins. These abnormal protein aggregates impair the functions of mitochondria and induce oxidative stress, thereby resulting in neuronal cell death. In turn, neuronal damage induces chr...