Synthesis, activity evaluation, and pro-apoptotic properties of novel 1,2,4-triazol-3-amine derivatives as potent anti-lung cancer agents

In this study, a series of 4,5-bis(substituted phenyl)-4H-1,2,4-triazol-3-amine compounds was designed, synthesised, and evaluated to determine their potential as anti-lung cancer agents. According to the results of screening of lung cancer cell lines A549, NCI-H460, and NCI-H23 in vitro, most of th...

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Main Authors: Xian-yu Sun (Author), Chun-yan Zhong (Author), Qing-qing Qiu (Author), Zhen-wang Li (Author), Mei-yu Liu (Author), Xin Wang (Author), Cheng-hao Jin (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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