Predominant overexpression of CD25/FOXP3, IFN-γ, and suppressive cytokines in high-grade lesion samples infected with human papillomavirus

• Main Authors: Camila M. Bonin (Author), Cacilda T. J. Padovani (Author), Alda Maria T. Ferreira (Author), Leandro S. Ávila (Author), Ana Paula Machado (Author), Thiago T. M. Prata (Author), Carlos Eurico S. Fernandes (Author), Inês Aparecida Tozetti (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Introduction: Human papillomavirus (HPV) persistent infection is the leading cause of cervical cancer and its precursor lesions, and the inappropriate immune response is among the factors that contribute to viral persistence. This may be influenced by regulatory T (Treg) cells and the produ...