Optimization of Personalized Amlodipine Dosing Strategies for Children Based on Pharmacokinetic Data from Chinese Male Adults and PBPK Modeling

For children, a special population who are continuously developing, a reasonable dosing strategy is the key to clinical therapy. Accurate dose predictions can help maximize efficacy and minimize pain in pediatrics. <b>Methods:</b> This study collected amlodipine pharmacokinetics (PK) dat...

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Main Authors: Xiaolu Han (Author), Xiaoxuan Hong (Author), Xianfu Li (Author), Yuxi Wang (Author), Zengming Wang (Author), Aiping Zheng (Author)
Format: Book
Published: MDPI AG, 2021-10-01T00:00:00Z.
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