Chloramphenicol Derivatives as Antibacterial and Anticancer Agents: Historic Problems and Current Solutions

• Auteurs principaux: George P. Dinos (Auteur), Constantinos M. Athanassopoulos (Auteur), Dionissia A. Missiri (Auteur), Panagiota C. Giannopoulou (Auteur), Ioannis A. Vlachogiannis (Auteur), Georgios E. Papadopoulos (Auteur), Dionissios Papaioannou (Auteur), Dimitrios L. Kalpaxis (Auteur)
• Format: Livre
• Publié: MDPI AG, 2016-06-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Chloramphenicol (CAM) is the D-threo isomer of a small molecule, consisting of a p-nitrobenzene ring connected to a dichloroacetyl tail through a 2-amino-1,3-propanediol moiety. CAM displays a broad-spectrum bacteriostatic activity by specifically inhibiting the bacterial protein synthesis. In certa...