External Evaluation of Population Pharmacokinetics Models of Lithium in the Bipolar Population

• Главные авторы: Lereclus Aurélie (Автор), Boniffay Andréa (Автор), Kallée Gauvind (Автор), Blin Olivier (Автор), Belzeaux Raoul (Автор), Frédéric Dayan (Автор), Benito Sylvain (Автор), Guilhaumou Romain (Автор)
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• Опубликовано: MDPI AG, 2023-11-01T00:00:00Z.
• Предметы: article
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Lithium has been used in the treatment of bipolar disorder for several decades. Treatment optimization is recommended for this drug, due to its narrow therapeutic range and a large pharmacokinetics (PK) variability. In addition to therapeutic drug monitoring, attempts have been made to predict indiv...