The protective effects of 18β-glycyrrhetinic acid against inflammation microenvironment in gastric tumorigenesis targeting PGE2-EP2 receptor-mediated arachidonic acid pathway

• Main Authors: Donghui Cao (Author), Jing Jiang (Author), Dan Zhao (Author), Menghui Wu (Author), Houjun Zhang (Author), Tianyu Zhou (Author), Tetsuya Tsukamoto (Author), Masanobu Oshima (Author), Quan Wang (Author), Xueyuan Cao (Author)
• Format: Book
• Published: SAGE Publishing, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Accumulating epidemiological and clinical evidence shows that inflammation is an important risk factor for gastrointestinal diseases. Glycyrrhiza glabra , a traditional Chinese medicine, has been shown to safely suppress gastric cancer; however, the anti-inflammatory mechanisms in gastric tumorigene...