Impact of genital warts on health related quality of life in men and women in mainland China: a multicenter hospital-based cross-sectional study

• Main Authors: Shi Ju-Fang (Author), Kang Dian-Ju (Author), Qi Shu-Zhen (Author), Wu Hai-Yan (Author), Liu Yan-Chun (Author), Sun Li-Jun (Author), Li Li (Author), Yang Ying (Author), Li Qing (Author), Feng Xiang-Xian (Author), Zhang Li-Qin (Author), Li Jie (Author), Li Xiao-Li (Author), Yang Yun (Author), Niyazi Mayinuer (Author), Xu Ai-Di (Author), Liu Jia-Hua (Author), Xiao Qing (Author), Li Lian-Kun (Author), Wang Xin-Zheng (Author), Qiao You-Lin (Author)
• Format: Book
• Published: BMC, 2012-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

<p>Abstract</p> <p>Background</p> <p>Information on the health-related quality of life (HRQoL) of patients with genital warts (GW) in populations in mainland China is still limited. The aim of the study was to use a generic instrument to measure the impact of genital warts on HRQoL in men and women in this setting.</p> <p>Methods</p> <p>A multi-centre hospital-based cross-sectional study across 18 centers in China was conducted to interview patients using the European quality of life-5 dimension (EQ-5D) instrument; respondents' demographic and clinical data were also collected.</p> <p>Results</p> <p>A total of 1,358 GW patients (612 men, 746 women) were included in the analysis, with a mean age of 32.0 ± 10.6 years. 56.4% of the patients reported some problems in the dimension of Anxiety/Depression (highest), followed by Pain/Discomfort (24.7%) and Mobility (3.5%). The overall visual analogue scale (VAS) score of the study population was found to be 65.2 ± 22.0, and the EQ-5D index score was found to be 0.843 ± 0.129 using Japanese preference weights (the Chinese preference was unavailable yet). Patients with lower VAS means and EQ-5D index scores were more often female, living in urban area, and suffering multiple GW (all p values < 0.05), but the values did not differ notably by age (p values > 0.05).</p> <p>Conclusions</p> <p>The HRQoL of patients with GW was substantially lower, compared to a national representative general population in China (VAS = ~80); the findings of different subgroups are informative for future GW prevention and control efforts.</p>

Item Description

10.1186/1471-2458-12-153
1471-2458