Handelin alleviates cachexia‐ and aging‐induced skeletal muscle atrophy by improving protein homeostasis and inhibiting inflammation

• Main Authors: Hui‐Jie Zhang (Author), Ben‐Hui Wang (Author), Xiang Wang (Author), Chun‐Ping Huang (Author), Si‐Man Xu (Author), Jia‐Li Wang (Author), Tian‐E Huang (Author), Wan‐Li Xiao (Author), Xiao‐Li Tian (Author), Xin‐Qiang Lan (Author), Qi‐Quan Wang (Author), Yang Xiang (Author)
• Format: Book
• Published: Wiley, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Handelin is a bioactive compound from Chrysanthemum indicum L. that improves motor function and muscle integrity during aging in Caenorhabditis elegans. This study aimed to further evaluate the protective effects and molecular mechanisms of handelin in a mouse muscle atrophy mode...