Interferon Regulatory Factor 8 Expressed in Microglia Contributes to Tactile Allodynia Induced by Repeated Cold Stress in Rodents

• Główni autorzy: Takanori Akagi (Autor), Yuta Matsumura (Autor), Masaya Yasui (Autor), Emiko Minami (Autor), Hidemasa Inoue (Autor), Takahiro Masuda (Autor), Hidetoshi Tozaki-Saitoh (Autor), Tomohiko Tamura (Autor), Kazue Mizumura (Autor), Makoto Tsuda (Autor), Hiroshi Kiyama (Autor), Kazuhide Inoue (Autor)
• Format: Książka
• Wydane: Elsevier, 2014-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract.: We investigated the role of interferon regulatory factor 8 (IRF8) in a model of chronic pain in which repeated cold stress (RCS) exposure produces tactile allodynia. RCS exposure produced a decrease in paw withdrawal threshold (PWT) to mechanical stimulation. Spinal microglia of RCS-expos...