Design and Optimization of Orally Administered Luteolin Nanoethosomes to Enhance Its Anti-Tumor Activity against Hepatocellular Carcinoma

• Main Authors: Mahmoud M. A. Elsayed (Author), Tarek M. Okda (Author), Gamal M. K. Atwa (Author), Gamal A. Omran (Author), Atef E. Abd Elbaky (Author), Abd El hakim Ramadan (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Luteolin (LUT) is a natural flavonoid with low oral bioavailability with restricted clinical applications due to its low solubility. LUT shows significant anti-tumor activity in many cancer cells, including hepatocellular carcinoma (HCC). The most recent trend in pharmaceutical innovations is the ap...