Development of Alectinib-Suspended SNEDDS for Enhanced Solubility and Dissolution

• Main Authors: Eun Ji Park (Author), Seung Ah Choi (Author), Kyoung Ah Min (Author), Jun-Pil Jee (Author), Sung Giu Jin (Author), Kwan Hyung Cho (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alectinib hydrochloride (ALH), a tyrosine kinase inhibitor, is a practically water-insoluble drug classified as BCS class IV. The present study aimed to develop novel suspended self-nanoemulsifying drug delivery system (Su-SNEDDS) to enhance the solubility and dissolution rate. The Su-SNEDDS was pre...