Mutation analysis of the cathepsin C gene in Indian families with Papillon-Lefèvre syndrome

• Main Authors: Srivastava Satish (Author), Sethuraman Gomathy (Author), Sathyan Parthasarathy (Author), Prasad Pullabatla (Author), Markandaya Manjunath (Author), Selvaraju Veeriah (Author), Thakker Nalin (Author), Kumar Arun (Author)
• Format: Book
• Published: BMC, 2003-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>PLS is a rare autosomal recessive disorder characterized by early onset periodontopathia and palmar plantar keratosis. PLS is caused by mutations in the cathepsin C (<it>CTSC</it>) gene. Dipeptidyl-peptidase I encoded by...