Therapeutic material basis and underling mechanisms of Shaoyao Decoction-exerted alleviation effects of colitis based on GPX4-regulated ferroptosis in epithelial cells

• Main Authors: Juan Li (Author), Xiangge Tian (Author), Jinming Liu (Author), Yuying Mo (Author), Xiaoyi Guo (Author), Yang Qiu (Author), Yuejian Liu (Author), Xiaochi Ma (Author), Yan Wang (Author), Yongjian Xiong (Author)
• Format: Book
• Published: BMC, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Shaoyao Decoction (SYD) is a canonical herbal medicine prescription formulated by Liu Wan-Su in AD 1186. SYD has been widely used to treat inflammatory bowel disease by clearing heat and damp, removing stasis toxin in the intestine; however, the precise mechanisms and therapeutic...