Formulation and Evaluation of pH-Modulated Amorphous Solid Dispersion-Based Orodispersible Tablets of Cefdinir

Formulation and Evaluation of pH-Modulated Amorphous Solid Dispersion-Based Orodispersible Tablets of Cefdinir

Cefdinir (CEF) is a semi-synthetic third-generation broad-spectrum oral cephalosporin that exhibits poor solubility at lower pH values. Considering this, pH-modulated CEF solid dispersions (ASDs) were produced by solvent evaporation method employing various hydrophilic carriers and alkalizers. Among...

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Main Authors: Yahya Alhamhoom (Author), Thanusha Kumaraswamy (Author), Avichal Kumar (Author), Shivakumar Hagalavadi Nanjappa (Author), Sanjana S. Prakash (Author), Mohamed Rahamathulla (Author), Kamal Y. Thajudeen (Author), Mohammed Muqtader Ahmed (Author), Thippeswamy Boreddy Shivanandappa (Author)
Format: Book
Published: MDPI AG, 2024-06-01T00:00:00Z.
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