Novel mouse model for evaluating in vivo efficacy of xCT inhibitor

• Main Authors: Ryosuke Yoshioka (Author), Yusuke Fujieda (Author), Yamato Suzuki (Author), Osamu Kanno (Author), Asako Nagahira (Author), Tomohiro Honda (Author), Masao Murakawa (Author), Hiroshi Yukiura (Author)
• Format: Book
• Published: Elsevier, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

xCT, a well-known cystine transporter, is reported to be involved in the proliferation of various cells, such as cancer cells, immune cells, and fibroblasts. xCT inhibitor is expected to be a promising drug for cancer or immune diseases. However, there are little studies reporting that xCT inhibitor...