Effectiveness and safety of canakinumab in cryopyrin-associated periodic syndrome: a retrospective study in China

• Main Authors: Xiaona Zhu (Author), Jiaqi Fan (Author), Yanyan Huang (Author), Yongbin Xu (Author), Zhi Yang (Author), Ruohang Weng (Author), Ying Luo (Author), Jun Yang (Author), Tingyan He (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective Cryopyrin-associated periodic syndrome (CAPS) is characterized by excessive IL-1β release resulting in systemic and organ inflammation. As an anti-IL-1 agent, canakinumab has been approved with all CAPS phenotypes in USA and European countries. However, the use of canakinumab in C...