CRISPR-mediated Transfection of Brugia malayi.
The application of reverse genetics in the human filarial parasites has lagged due to the difficult biology of these organisms. Recently, we developed a co-culture system that permitted the infective larval stage of Brugia malayi to be transfected and efficiently develop to fecund adults. This was e...
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Public Library of Science (PLoS),
2020-08-01T00:00:00Z.
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