Synergisitic anti-colorectal cancer effects of WNT974 combined with artesunate via cooperative regulation of p21, p27, and AKT

• Главные авторы: Rui-Hong Gong (Автор), Minting Chen (Автор), Chunhua Huang (Автор), Hoi Leong Xavier Wong (Автор), Sibao Chen (Автор), Zhaoxiang Bian (Автор), Guo-Qing Chen (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2024-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Objective: To evaluate the synergistic effects and underlying mechanisms of WNT974 and artesunate (ART) combination therapy in the treatment of colorectal cancer (CRC). Methods: We conducted an initial assessment of the synergistic impact of WNT974 and ART on cell viability using the MTT assay acros...