Synergisitic anti-colorectal cancer effects of WNT974 combined with artesunate via cooperative regulation of p21, p27, and AKT

• Main Authors: Rui-Hong Gong (Author), Minting Chen (Author), Chunhua Huang (Author), Hoi Leong Xavier Wong (Author), Sibao Chen (Author), Zhaoxiang Bian (Author), Guo-Qing Chen (Author)
• Format: Book
• Published: Elsevier, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To evaluate the synergistic effects and underlying mechanisms of WNT974 and artesunate (ART) combination therapy in the treatment of colorectal cancer (CRC). Methods: We conducted an initial assessment of the synergistic impact of WNT974 and ART on cell viability using the MTT assay acros...