Role of Tissue-Type Plasminogen Activator in Ischemic Stroke
Tissue-type plasminogen activator (t-PA) administration has been approved for treating acute ischemic stroke, but delayed treatment is associated with increased risk of cerebral hemorrhage and brain injury. t-PA, a serine proteinase, converts plasminogen to plasmin. Plasmin participates not only in...
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Elsevier,
2010-01-01T00:00:00Z.
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