Rapamycin maintains the primordial follicle pool and protects ovarian reserve against cyclophosphamide-induced damage
Any abnormal activation of primordial follicles and subsequent depletion can irreversibly diminish the ovarian reserve, which is one of the major chemotherapy-induced adverse effects in young patients with cancer. Herein, we investigated the effects of rapamycin on the activation and development of...
Saved in:
Main Authors: | Xiuying CHEN (Author), Zhijing TANG (Author), Haiyun GUAN (Author), Hexia XIA (Author), Chao GU (Author), Yan XU (Author), Bin LI (Author), Wei ZHANG (Author) |
---|---|
Format: | Book |
Published: |
The Society for Reproduction and Development,
2022-06-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Rapamycin Prevents cyclophosphamide-induced Over-activation of Primordial Follicle pool through PI3K/Akt/mTOR Signaling Pathway in vivo
by: Linyan Zhou, et al.
Published: (2017) -
Sohlh1 and Lhx8 are prominent biomarkers to estimate the primordial follicle pool in mice
by: Li Liu, et al.
Published: (2023) -
The ovaries of transgender men indicate effects of high dose testosterone on the primordial and early growing follicle pool
by: Emily Bailie, et al.
Published: (2023) -
Comparison of methods for quantifying primordial follicles in the mouse ovary
by: Urooza C. Sarma, et al.
Published: (2020) -
Kisspeptin regulates the development of caprine primordial follicles in vitro
by: Manjula Priyantha Sumith Magamage, et al.
Published: (2021)