Lipid and Peptide-Oligonucleotide Conjugates for Therapeutic Purposes: From Simple Hybrids to Complex Multifunctional Assemblies
Antisense and small interfering RNA (siRNA) oligonucleotides have been recognized as powerful therapeutic compounds for targeting mRNAs and inducing their degradation. However, a major obstacle is that unmodified oligonucleotides are not readily taken up into tissues and are susceptible to degradati...
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Main Authors: | Carme Fàbrega (Author), Anna Aviñó (Author), Natalia Navarro (Author), Andreia F. Jorge (Author), Santiago Grijalvo (Author), Ramon Eritja (Author) |
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Format: | Book |
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MDPI AG,
2023-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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