Enhancement of the Bioavailability and Anti-Inflammatory Activity of Glycyrrhetinic Acid via Novel Soluplus^®-A Glycyrrhetinic Acid Solid Dispersion

• Main Authors: Hao Wang (Author), Runwei Li (Author), Yuan Rao (Author), Saixing Liu (Author), Chunhui Hu (Author), Yong Zhang (Author), Linchao Meng (Author), Qilin Wu (Author), Qiuhong Ouyang (Author), Hao Liang (Author), Meng Qin (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glycyrrhetinic acid (GA) is an anti-inflammatory drug with potential for development. However, the poor solubility of GA in water leads to extremely low bioavailability, which limits its clinical applications. Solid dispersions have become some of the most effective strategies for improving the solu...