Targeted next-generation sequencing of 21 candidate genes in hereditary ovarian cancer patients from the Republic of Bashkortostan

• Main Authors: D. S. Prokofyeva (Author), E. T. Mingazheva (Author), Ya. V. Valova (Author), D. D. Sakaeva (Author), R. R. Faishanova (Author), A. Kh. Nurgalieva (Author), R. R. Valiev (Author), N. Bogdanova (Author), T. Dörk (Author), E. K. Khusnutdinova (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract About 5-10% of all ovarian cancer cases show familial clustering, and some 15-25% of familial ovarian cancer cases are mediated by high-penetrance mutations in the BRCA1 and BRCA2 genes. Only few other genes have been identified for familial ovarian cancer. We conducted targeted next-genera...