Development and validation of a novel method for simultaneous quantification of enzalutamide, darolutamide and their active metabolites in mice dried blood spots using LC-MS/MS: Application to pharmacokinetic study in mice

• Päätekijät: Neeraj Kumar Saini (Tekijä), Suresh P Sulochana (Tekijä), Mohd Zainuddin (Tekijä), Ramesh Mullangi (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: International Association of Physical Chemists (IAPC), 2018-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

A simple, sensitive and rapid assay method has been developed and validated for the estimation of enzalutamide, N-desmethylenzalutamide (active metabolite of enzalutamide), darolutamide and ORM-15341 (active metabolite of darolutamide) on mice dried blood spots (DBS) using liquid chromatography coup...