Development and validation of a novel method for simultaneous quantification of enzalutamide, darolutamide and their active metabolites in mice dried blood spots using LC-MS/MS: Application to pharmacokinetic study in mice

A simple, sensitive and rapid assay method has been developed and validated for the estimation of enzalutamide, N-desmethylenzalutamide (active metabolite of enzalutamide), darolutamide and ORM-15341 (active metabolite of darolutamide) on mice dried blood spots (DBS) using liquid chromatography coup...

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Main Authors: Neeraj Kumar Saini (Author), Suresh P Sulochana (Author), Mohd Zainuddin (Author), Ramesh Mullangi (Author)
Format: Book
Published: International Association of Physical Chemists (IAPC), 2018-09-01T00:00:00Z.
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