Screening of Graves' disease susceptibility genes by whole exome sequencing in a three-generation family

• Main Authors: Zhuoqing Hu (Author), Wei Li (Author), Miaosheng Li (Author), Hao Wei (Author), Zhihui Hu (Author), Yanting Chen (Author), Ai Luo (Author), Wangen Li (Author)
• Format: Book
• Published: BMC, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Graves' disease(GD) has a tendency for familial aggregation, but it is uncommon to occur in more than two generations. However, little is known about susceptibility genes for GD in the three-generation family. Methods DNA were extracted from three-generation familial GD pati...