Preparation and characterization of Alendronate depot microspheres based on novel poly(-ε-caprolactone)/Vitamin E TPGS copolymers

• প্রধান লেখক: Christina Koulouktsi (লেখক), Stavroula Nanaki (লেখক), Panagiotis Barmpalexis (লেখক), Margaritis Kostoglou (লেখক), Dimitrios Bikiaris (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2019-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

In the present study, new aledronate (AL) loaded microspheres were prepared with the use of polycaprolactone (PCL)/Vitamin E d-ɑ-tocopheryl poly(ethylene glycol) 1000 succinate (TPGS) copolymers. Specifically, PCL-TPGS copolymers, prepared at several PCL to TPGS ratios (namely, 90/10, 80/20, 70/30 a...