Parthenolide promotes expansion of Nestin+ progenitor cells via Shh modulation and contributes to post-injury cerebellar replenishment

• Main Authors: Dong Jinling (Author), Feng Liyuan (Author), Fu Wenying (Author), Huang Yuting (Author), Tang Xiangyu (Author), Huang Xiuning (Author), Tang Yu (Author), Ming Qianliang (Author), Guo Linming (Author), Gao Ning (Author), Li Peng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Regeneration of injuries occurring in the central nervous system is extremely difficult. Studies have shown that the developing cerebellum can be repopulated by a group of Nestin-expressing progenitors (NEPs) after irradiation injury, suggesting that modulating the mobilization of NEPs i...